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Senior Member
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Serum Neutralizing Activity of mRNA-1273 against SARS-CoV-2 Variants
引用:
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Results showed minimal effects on neutralization titers against the B.1.1.7 (Alpha) variant (1.2-fold reduction compared with D614G); other VOCs such as B.1.351 (Beta, including B.1.351-v1, B.1.351-v2, and B.1.351-v3), B.1.617.2 (Delta), and P.1 (Gamma) showed decreased neutralization titers ranging from 2.1-fold to 8.4-fold reductions compared with D614G, although all remained susceptible to mRNA-1273–elicited serum neutralization.
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6月28日發表的這篇研究
以上是說莫德納疫苗對Alpha變種的中和抗體效價(直翻應該是滴度、濃度，但概念是一樣的)跟武漢D614G比下降最小
其它變種有2.1~8.4倍的減效
參照它裡面的這張圖我夾在附件來看
G614G武漢株 效價1870
英國株Alpha 1599
南非株Beta 273、255、222
巴西株Gamma 588
印度株Delta 883
因為莫德納的mRNA劑量跟抗體效價本來就很高
雖然Delta 883跟武漢株1870比只剩下接近一半
但其實效價還是滿高的
比較差的是南非株…
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