CureVac 12mcg
Pfizer-Biontech 30mcg
Moderna 100mcg

多打一針可以救得回來嗎


https://www.sciencemag.org/news/202...accine-covid-19

Peter Kremsner of University Hospital Tübingen, who helped run the CureVac study, suggests another factor: too low a dose of vaccine. “I am uncertain what it was finally, natural uracil or only dose or both,” he says. Kremsner helped conduct CureVac’s phase 1 study, which compared the safety and immune responses generated by doses between 2 and 20 micrograms. The study revealed the company should not use the higher doses “because of intolerability, perhaps due to natural uracil?” he says. (Kremsner says he hopes to publish his work soon, but a preprint with some of the study’s data has already been posted.) CureVac settled on 12 micrograms, a dose that balanced the best safety profile with the highest level of neutralizing antibodies. (The Pfizer-BioNTech vaccine uses a 30-microgram dose and Moderna’s is 100 micrograms.)