The An-140 has suffered six major incidents, including four crashes with total loss of life.

On 23 December 2002, an Aeromist Kharkiv An-140 carrying many of Ukraine's top aviation designers and engineers crashed into a mountainside....

On 12 August 2005, a Safiran Airlines HESA IrAn-140 diverted to Arak International Airport due to an engine failure...
On 23 December 2005, Azerbaijan Airlines Flight 217, an Antonov An-140 4K-AZ48, plunged into the Caspian Sea about 20 miles north of the capital, Baku. All 18 passengers and five crew members died...

On 15 February 2006, an IrAn-140-100 (test registration HESA 90-04) crashed at Shahin Shahr, Isfahan Province, Iran, during a training flight.[19] All 5 pilots on board were killed...

On 06 September 2008, a South Airlines An-140 coming from Lviv, Ukraine, suffered a front landing gear failure...

On 10 August 2014, Sepahan Airlines (HESA) flight SPN 5915, crashed on take off...

這麼多的危險紀錄...