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以下原文節錄自 Harrison 內科學 15 edition
Treatment options for unresectable disease are limited. Randomized trials have not shown a survival advantage after chemoembolization. The liver cannot tolerate high doses of radiation. The disease is not responsive to chemotherapy, including newer agents such as gemcytabine. Investigative immunotherapy and gene therapy techniques have not yet been successful. Based on the presence of hormone receptors on the tumor, tamoxifen has been tested, but without success, and octreotide has had some modest activity. In patients with resectable tumors, polyprenoic acid (a retinoic acid formulation) and intraarterial 131I-labeled lipiodol have been reported to reduce the rate of recurrence.
基本上,無法手術的話,快去完成未完的事吧!化療有效的話,對延長生命有幫忙,但問題是某些化療藥物(並非全部)有較大的副作用,建議先和醫師問清楚副作用,再和老人家討論.......May God bless him!
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